description continues: 3)After reading Flier’s article and Chapter 14, think about the role of cellular and molecular biology in regulation of food intake and nutrition, energy homeostasis, and metabolism. Read a selection of the review articles from the list provided below. Each article provides an overview of the complex biochemical and molecular processes that help regulate different organ systems in health and in the development of diabetes and cardiovascular disease. Please note, you are expected to read a selection of the review articles listed below to gain a better or deeper understanding of the topic. However, for your Application Assignment you must also find primary research articles in your area of interest. You may use the review articles in your Application paper, but if you do not cite primary research as well, that will result in a deduction of points. Choose a focus or a specific area that interests you. You should then locate and use appropriate primary research articles for this Application. Obesity and Energy Homeostasis Cummings , D. E., & Overduin, J. (2007). Gastrointestinal regulation of food intake. Journal of Clinical Investigation, 117, 13–23. Retrieved from the Walden Library Academic Search Premier database. (AN 25218811) Drucker, D. J. (2006). The biology of incretin hormones. Cell Metabolism, 3, 153–165. Retrieved from http://www.pbrc.edu/huec7005/slides/10.23.article4.pdf Flier, J. S. (2004). Obesity wars: Molecular progress confronts an expanding epidemic. Cell, 116, 337–350. Click here to access the article. Hill, J. O. (2006). Understanding and addressing the epidemic of obesity: An energy balance perspective. Endocrine Reviews, 27, 750–761. Retrieved from http://edrv.endojournals.org/cgi/reprint/27/7/750 Nutrition, Obesity, and Atherosclerotic Cardiovascular Disease McGavock, J. M., Victor, R. G., Unger, R. H., & Szczepaniak, L. S. (2006). Adiposity of the heart, revisited. Annals of Internal Medicine, 144, 517–524. Retrieved from the Walden Library Academic Search Premier database. (AN 20371697) Semenkovich, C. F. (2006). Insulin resistance and atherosclerosis. Journal of Clinical Investigation, 116, 1813–1822. Retrieved from the Walden Library Academic Search Premier database. (AN 23151475) Berg, A. H., & Scherer, P. E. (2005). Adipose tissue, inflammation, and cardiovascular disease. Circulation Research, 96, 939–949. Retrieved from http://circres.ahajournals.org/cgi/reprint/96/9/939 Getz, G. S., & Reardon, C. A. (2007). Nutrition and cardiovascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 27, 2499–2506. Retrieved from http://atvb.ahajournals.org/cgi/reprint/27/12/2499 Katagiri, H., Yamada, T., & Oka, Y. (2007). Adiposity and cardiovascular disorders disturbance of the regulatory system consisting of humoral and neuronal signals. Circulation Research, 101, 27–39. Retrieved from http://circres.ahajournals.org/cgi/content/abstract/101/1/27 Lopaschuk, G. D., Folmes, C. D. L., & Stanley, W. C. (2007). Cardiac energy metabolism in obesity. Circulation Research, 101, 335–347. Retrieved from http://circres.ahajournals.org/cgi/reprint/101/4/335 Obesity and Inflammation Shoelson, S. E., Herrero, L., & Naaz, A. (2007). Obesity, inflammation, and insulin resistance. Gastroenterology, 132, 2169–2180. Retrieved from http://www.jci.org/116/7/1793/pdf Corvera, S., Burkart, A., Kim, J.-Y., Christianson, J., Wang, Z., & Scherer, P. E. (2006). Keystone meeting summary: ‘Adipogenesis, obesity, and inflammation’ and ‘Diabetes mellitus and the control of cellular energy metabolism,’ January 21–26, 2006, Vancouver, Canada. Genes & Development, 20, 2193–2201. Retrieved from http://www.genesdev.org/cgi/reprint/20/16/2193 Metabolic Syndrome Bagby, S. P. (2004). Obesity-initiated metabolic syndrome and the kidney: A recipe for chronic kidney disease? Journal of the American Society of Nephrology, 15, 2775–2791. Retrieved from http://jasn.asnjournals.org/cgi/reprint/15/11/2775 Unger, R. H. (2003). Minireview: Weapons of lean body mass destruction: The role of ectopic lipids in the metabolic syndrome. Endocrinology, 144, 5159–5165. Retrieved from http://endo.endojournals.org/cgi/reprint/144/12/5159 Write a three to five page (body; double spaced) review of the topic from a public health biology perspective. You may use additional resources as needed. In your review, include the following: - The biological basis of energy homeostasis; - Discuss the recent and current research on this issue, focusing on your area of interest; - Explain the application of this information to public health, providing some examples of how this information is used in public health policy, programs, and practice.